Detalhe da pesquisa
1.
Estrogen receptor gets a grip on RNA.
Cell
; 184(20): 5086-5088, 2021 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34559987
2.
Dual-mechanism estrogen receptor inhibitors.
Proc Natl Acad Sci U S A
; 118(35)2021 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-34452998
3.
Targeting the oncogenic transcription factor FOXM1 to improve outcomes in all subtypes of breast cancer.
Breast Cancer Res
; 25(1): 76, 2023 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37370117
4.
Effective combination treatments for breast cancer inhibition by FOXM1 inhibitors with other targeted cancer drugs.
Breast Cancer Res Treat
; 198(3): 607-621, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-36847915
5.
Contrasting activities of estrogen receptor beta isoforms in triple negative breast cancer.
Breast Cancer Res Treat
; 185(2): 281-292, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-33001337
6.
Suppression of breast cancer metastasis and extension of survival by a new antiestrogen in a preclinical model driven by mutant estrogen receptors.
Breast Cancer Res Treat
; 181(2): 297-307, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-32277377
7.
Full antagonism of the estrogen receptor without a prototypical ligand side chain.
Nat Chem Biol
; 13(1): 111-118, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27870835
8.
Non-nuclear estrogen receptor alpha activation in endothelium reduces cardiac ischemia-reperfusion injury in mice.
J Mol Cell Cardiol
; 107: 41-51, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28457941
9.
The Activation Function-1 of Estrogen Receptor Alpha Prevents Arterial Neointima Development Through a Direct Effect on Smooth Muscle Cells.
Circ Res
; 117(9): 770-8, 2015 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26316608
10.
The anticancer potential of steroidal saponin, dioscin, isolated from wild yam (Dioscorea villosa) root extract in invasive human breast cancer cell line MDA-MB-231 in vitro.
Arch Biochem Biophys
; 591: 98-110, 2016 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26682631
11.
Ligand Accessibility and Bioactivity of a Hormone-Dendrimer Conjugate Depend on pH and pH History.
J Am Chem Soc
; 137(32): 10326-35, 2015 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26186415
12.
The forkhead transcription factor FOXM1 promotes endocrine resistance and invasiveness in estrogen receptor-positive breast cancer by expansion of stem-like cancer cells.
Breast Cancer Res
; 16(5): 436, 2014 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25213081
13.
Integrative genomics of gene and metabolic regulation by estrogen receptors α and ß, and their coregulators.
Mol Syst Biol
; 9: 676, 2013 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-23774759
14.
Erratum: Full antagonism of the estrogen receptor without a prototypical ligand side chain.
Nat Chem Biol
; 13(6): 691, 2017 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28514419
15.
Corrigendum: Full antagonism of the estrogen receptor without a prototypical ligand side chain.
Nat Chem Biol
; 13(6): 691, 2017 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28514424
16.
Mechanisms enforcing the estrogen receptor ß selectivity of botanical estrogens.
FASEB J
; 27(11): 4406-18, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23882126
17.
NB compounds are potent and efficacious FOXM1 inhibitors in high-grade serous ovarian cancer cells.
J Ovarian Res
; 17(1): 94, 2024 May 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38704607
18.
Reprogramming of endothelial gene expression by tamoxifen inhibits angiogenesis and ERα-negative tumor growth.
Theranostics
; 14(1): 249-264, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38164151
19.
Asymmetric Allostery in Estrogen Receptor-α Homodimers Drives Responses to the Ensemble of Estrogens in the Hormonal Milieu.
bioRxiv
; 2024 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38645081
20.
Somatic estrogen receptor α mutations that induce dimerization promote receptor activity and breast cancer proliferation.
J Clin Invest
; 134(1)2024 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37883178